Several references stating non porphyrinogenicity of glucocorticoids.

(To be edited, initial data ST OCT 04) Extra strong glucocorticoid salve 0.005% and creme 0,05% used in dermatology. Risk for systemic exposure in application on large areas of the skin. Glucocorticoid: South African list: use Kalman, Bonkovsky: believed to be safe The Merck Manual: use Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997: safe Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncan’s Diseases of Metabolism, Philadelphia, WB Saunders 1980, p 939.: safe

Uneventful use reported in 4 patientS with acute porphyria.