Not metabolised.

(To be edited, initial data ST OCT 04) Water-soluble methyl cyclohexane acetic acid structural analogue to GABA, used in additional treatment in all types of partial epilepsy. No first passage metabolism, excreted in unchanged form in urine. EPI-list: safe. South African list: use. French list: authorized. See: Tatum and Zachariah: Gabapentin treatment of seizures in acute intermittent porphyria. Neurology 1995; 45:1216-7. C.Andersson; patient report: tolerated (n=1) Used in porphyria wards (Sweden).

Uneventful use reported in 25 patients with acute porphyria.