Compare the neuroleptic benzodiazepine clozapine :

(To be edited, initial data ST OCT 04) Benzodiazepine derivative used in schizophrenia. Metabolized via CYP 1A2 and 2D6. No indications of CYP-inducing effects. Thunell; clinical experience from prolonged treatment (n=1):no porphyric side effects See Holoryd S et al. Psychotropic drugs in acute…(one case) (PMID: 10511069).

Uneventful use reported in 3 patients with acute porphyria.