Not CYP-metabolised. No data pointing to CYP-induction. References consider it safe.

(To be edited, initial data ST OCT 04) Narcotic psychostimulant used in treatment of attention deficit hyperactivity (ADH). Metabolized by de-esterification to alphaphenylpiperidine acetic acid. No data pointing to CYP-induction. EPI-list: safe. South African list: use. Australian list: safe.

Uneventful use reported in 2 patients with acute porphyria.