Insufficient data on metabolism. Compare loratadine (R06A X13): "Metabolised by CYP 3A4. Inducer of CYP 3A4. Two references consider it safe. Clinical experience (Swedish) seems to point to non-porphyrinogenicity. "

(To be edited, initial data ST OCT 04) Dibencycloheptene methylpiperadine antihistamine, also effective against itching in neurodermatitis. Main metabolite is the glucuronide conjugate of the drug. Is also excreted in unchanged form in faeces. Structural analogue to loratidine. French list: authorized