Monograph
C10AB04 - Gemfibrozil |
Propably not porphyrinogenic |
PNP |
Rationale
Substrate of CYP 3A4. No data pointing to CYP-inducing properties. One reference: use with care. Occasional observations of non-porphyrinogenicity.
Chemical description
Fibric acid derivative used (1200 mg/d) in hyperlipidemia. Longacting. Metabolized by CYP 3A4; inhibitor of CYPs 1A2 (weak), 2C19, 2C8, 2C9. No data point to CYP-induction. Thunell, patient report (n=2): tolerated. South African list: use with care
Similar drugs
Tradenames
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Gemfibrozil Auro 600 mg, filmomhulde tabletten · Lopid 300 mg, harde capsules · Lopid 450 mg, filmomhulde tabletten · Lopid 600, filmomhulde tabletten 600 mg · Lopid 900, filmomhulde tabletten 900 mg 
Gemfibrozilo · GEMFIBROZILO ARISTO 600 mg COMPRIMIDOS RECUBIERTOS CON PEL?CULA EFG · GEMFIBROZILO STADA 600 mg COMPRIMIDOS EFG · GEMFIBROZILO STADA 900 mg COMPRIMIDOS EFG · GEMFIBROZILO TARBIS 600 mg COMPRIMIDOS RECUBIERTOS CON PELICULA EFG · GEMFIBROZILO TARBIS 900 mg COMPRIMIDOS RECUBIERTOS CON PELICULA EFG · LOPID 600 mg COMPRIMIDOS RECUBIERTOS CON PELICULA · LOPID 900 mg COMPRIMIDOS RECUBIERTOS CON PELICULA · TRIALMIN 600 mg COMPRIMIDOS RECUBIERTOS CON PELICULA · TRIALMIN 900 mg COMPRIMIDOS RECUBIERTOS CON PELICULA 
Gemfibrozil · Genlip · Lopid 
Gemfibrozil · Lopid 
Lopid 
Lopid 
Lopid
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