D07AB08 - Desonide |
Not porphyrinogenic |
NP |
Rationale
Several references stating non-porphyrinogenicity of glucocorticoids.
Chemical description
Glucocorticoid used in dermatology. Systemic exposure in application on large areas of the skin. Glucocorticoid: South African list: use. Kalman, Bonkovsky: believed to be safe. The Merck Manual: use. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncan’s Diseases of Metabolism, Philadelphia, WB Saunders 1980, p 939: safe.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Management of acute attacks in the porphyrias.
Kalman DR, Bonkovsky HL. Clin Dermatol. 1998; 16(2):299-306.
|
9554242 |
| 2. | Drugs in the acute porphyrias--toxicogenetic diseases.
Moore MR, Hift RJ. Cell Mol Biol (Noisy-le-grand). 1997 Feb; 43(1):89-94.
|
9074793 |
| Other sources | ||
| 3. | Porphyrin metabolism and the Porphyrias [Book Chapter]
Tschudy DP, Lamon JM Bondy BK, Rosenberg LE (eds): Duncan's Diseases of Metabolism, Philadelphia, WB Saunders. 1980.
|
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Tradenames
Locapred · Locatop · Tridesonit 
Nutragent 
Apolar · Locatop · Zotinar 
Locatop 
Dermosupril · Desoderm · Desokort · Desonida · Desotopic · Itrocsona · Locorten · Tresilenal 
Desowen 
Desowen 
Desonide 
Apolar