A03BA01 - Atropine |
Probably not porphyrinogenic |
PNP |
Rationale
Alkaloid, probably insignificant hepatic load. Five references: safe.
Chemical description
Tertiary amine alcaloide used preoperatively,and in bradycardia, hypersecretion and spastic intestinal conditions, parenterally administered 0.4-0.5 mg. South African list: use. French list: authorized. Kalman/Bonkovski: Believed to be safe. Moore/Hift: safe. Eales: safe.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Porphyria and the dangerous life-threatening drugs.
Eales L. S Afr Med J. 1979 Nov; 56(22):914-7.
|
515871 |
| 2. | Management of acute attacks in the porphyrias.
Kalman DR, Bonkovsky HL. Clin Dermatol. 1998; 16(2):299-306.
|
9554242 |
| 3. | Drugs in the acute porphyrias--toxicogenetic diseases.
Moore MR, Hift RJ. Cell Mol Biol (Noisy-le-grand). 1997 Feb; 43(1):89-94.
|
9074793 |
| Other sources | ||
| 4. | French List
Centre Français des Porphyries
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Tradenames