Monograph H02AB04 - Methylprednisolone
Possibly porphyrinogenic
PSP
Rationale
Glucocorticoid. Substrate, inhibitor and activator / stimulator of CYP 3A4. Several references consider it safe.
Chemical description
Glucocorticoid for intramuscular administration or local injection. Metabolized by CYP 3A4. Glucocorticoids: South African list: use. French list: authorized. Kalman, Bonkowsky: probably safe Michael Moore's list: safe. The Merck Manual: safe. Tschudy DP, Lamon JM: Porphyrin metabolism and the Porphyrias in Bondy BK, Rosenberg LE (eds): Duncan’s Diseases of Metabolism, Philadelphia, WB Saunders. 1980,p 939. :safe. Moore MR, Hift RJ: Drugs in acute porphyria. Cell Mol Biol 43:89, 1997:safe
Similar drugs
Tradenames
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Depo-Medrol 40 mg/ml, suspensie voor injectie · Methylprednisolon ACE 100 mg tabletten · Methylprednisolon Eureco-Pharma 62,5 mg/ml poeder en oplosmiddel voor oplossing voor injectie · Methylprednisolon Eureco-Pharma poeder voor oplossing voor infusie, 1000 mg · Methylprednisolon Eureco-Pharma poeder voor oplossing voor infusie, 500 mg · Methylprednisolon Eurogenerics 16 mg tabletten · Methylprednisolon Eurogenerics 4 mg tabletten · Solu-Medrol 40mg/ml, poeder en oplosmiddel voor oplossing voor injectie · Solu-Medrol 62,5mg/ml, poeder en oplosmiddel voor oplossing voor injectie · Solu-Medrol, poeder voor oplossing voor infusie, 500 mg en 1000 mg Depo-Medrol · Depo-Medrol + Lidocaine · Depo-Medrol + Lidocaine 40 mg/ml - 10 mg/ml susp. inj. p.artic./i.l?s./i.artic./i.burs. flac. · Depo-Medrol 200 mg/5 ml susp. inj. p.artic./i.l?s./i.artic./i.burs./i.m. flac. · Depo-Medrol 40 mg/1 ml susp. inj. p.artic./i.l?s./i.artic./i.burs./i.m. flac. · Depo-Medrol 40 mg/1 ml susp. inj. p.artic./i.l?s./i.artic./i.burs./i.m. ser. pr?remplie · Depo-Medrol 80 mg/2 ml susp. inj. p.artic./i.l?s./i.artic./i.burs./i.m. flac. · Depo-Medrol 80 mg/2 ml susp. inj. p.artic./i.l?s./i.artic./i.burs./i.m. ser. pr?remplie · Medrol 32 mg comp. · Medrol 4 mg comp. · Medrol A 16 mg comp. · Medrol Pak 4 mg comp. · Methylprednisolon Ace Pharmaceuticals 100 mg comp. · Solu-Medrol 1 000 mg sol. inj. (pdr. + solv.) i.v./i.m. flac. · Solu-Medrol 500 mg sol. inj. (pdr. + solv.) i.v./i.m. flac. · Solu-Medrol S.A.B. 1 000 mg sol. inj. (pdr. + solv.) i.v./i.m. flac. · Solu-Medrol S.A.B. 125 mg sol. inj. (pdr. + solv.) i.v./i.m. flac. · Solu-Medrol S.A.B. 40 mg sol. inj. (pdr. + solv.) i.v./i.m. amp. flac. · Solu-Medrol S.A.B. 500 mg sol. inj. (pdr. + solv.) i.v./i.m. · Solu-Medrol S.A.B. Act-O-Vial 125 mg sol. inj. (pdr. + solv.) i.v./i.m. flac. · Solu-Medrol S.A.B. Act-O-Vial 250 mg sol. inj. (pdr. + solv.) i.v./i.m. flac. · Solu-Medrol S.A.B. Act-O-Vial 40 mg sol. inj. (pdr. + solv.) i.v./i.m. flac. Metilprednisolona · METILPREDNISOLONA NORMON 20 mg POLVO Y DISOLVENTE PARA SOLUCION INYECTABLE EFG · METILPREDNISOLONA NORMON 40 mg POLVO Y DISOLVENTE PARA SOLUCION INYECTABLE EFG · Metilprednisolona Orion 16 mg Comprimidos efg · Solu-Moderin · Solu-Moderin 1 g Polvo y Disolvente Para Soluci?n Inyectable · Solu-Moderin 40 mg Polvo y Disolvente Para Soluci?n Inyectable · Solu-Moderin 500 mg Polvo y Disolvente Para Soluci?n Inyectable · Urbason · URBASON 16 mg COMPRIMIDOS · URBASON 250 mg POLVO Y DISOLVENTE PARA SOLUCION INYECTABLE O PARA PERFUSION · URBASON 4 mg COMPRIMIDOS · URBASON 40 mg COMPRIMIDOS · URBASON 40 mg POLVO Y DISOLVENTE PARA SOLUCION INYECTABLE · URBASON 8 mg POLVO Y DISOLVENTE PARA SOLUCION INYECTABLE Depomedrol · Medrol · Metildrol · Metilprednisolone · Solumedrol · Urbason LEMOD SOLU 125 mg · LEMOD SOLU 500 mg · MEDROL 32 mg · MEDROL 4 mg · MEDROL A 16 mg · METILPREDNISOLON ROMPHARM 250 mg · METILPREDNISOLON ROMPHARM 500 mg · Solu - Medrol act-o-Vial Depo-Medrone · Medrone · Methylprednisolone · Methylprednisolone sodium succinate · Solu-Medrone Depo-Medrol · Medrol · Methylprednisolone Orion · Solu-medrol Depo-Medrol · Medrol · Medrol unimedic · Methylprednisolone Orion · Metylprednisolon Aurora Medical · Solu-Medrol Depo-Medrol · Depo-Medrol z Lidokaina · Medrol · Meprelon · Methylprednisolone Sopharma · Metypred · Solu-Medrol Depo Medrol · Depo Medrol + Lidocaine · Medrol · Medrol pak · Medrol-a · Methylprednisolone EG · Solu-Medrol · Solu-Medrol s.a.b. · Solu-Medrol S.A.B. Act-O-Vial Depo-Medrol · Solu-Medrol Depo-Medrol · Medrol · Metypred · Solomet · Solomet Depot · Solu-Medrol Depo-Medrol · Medrol · Solu-Medrol Lemod® - Solu