Monograph

A04AA02 - Granisetron

Propably not porphyrinogenic

Rationale

Substrate for CYPs 3A4 and 3A5. No data pointing to clinical CYP-induction. One reference: authorised.

Chemical description

Selective 5-HT-antagonist used as prophylaxis or treatment of postoperative nausea and nausea under chemotherapy ; 2-9 mg/d perorally or parenterally. Metabolized mainly by CYP 3A4. No instances of CYP-induction observed clinically. South African list: No data/avoid. French list: authorized

IPNet drug reports

Uneventful use reported in 2 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes A04A / A04AA or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Granisetron · Granisetron Aurobindo 1 mg, filmomhulde tabletten · Granisetron Aurobindo 2 mg, filmomhulde tabletten · Granisetron Baxter 1 mg/ml, oplossing voor injectie · Granisetron Fresenius Kabi 1 mg/ml oplossing voor injectie · Granisetron Hikma, concentraat voor oplossing voor infusie, 1 mg/ml · Granisetron Hikma, oplossing voor injectie, 1 mg/ml · Granisetron Mylan 1 mg, filmomhulde tabletten · Granisetron Mylan 2 mg, filmomhulde tabletten · Granisetron-hameln 1 mg/ml, concentraat voor oplossing voor injectie of infusie · Kytril · Kytril 1 mg tabletten, omhulde tabletten · Kytril 2 mg tabletten, omhulde tabletten · Sancuso · Sancuso 3,1 mg/24 uur, pleister voor Transdermaal gebruik

Belgium

Granisetron · Granisetron Fresenius Kabi 1 mg/ml sol. inj./perf. (sol., à diluer) i.v. amp. · Kytril · Kytril 1 mg comp. · Kytril 3 mg/3 ml sol. inj. i.v. amp. · Sancuso · Sancuso 3.1 mg/24 h patch transderm. sachet

United Kingdom

Granisetron · Granisetron 1mg tablets · Granisetron 1mg/1ml concentrate for solution for injection ampoules · Granisetron 2mg tablets · Granisetron 3.1mg/24hours transdermal patches · Granisetron 3mg/3ml concentrate for solution for injection ampoules · Kytril · Kytril 1mg tablets · Kytril 1mg/1ml solution for injection ampoules · Kytril 200micrograms/ml liquid paediatric · Kytril 2mg tablets · Kytril 3mg/3ml solution for injection ampoules · Sancuso · Sancuso 3.1mg/24hours transdermal patches

Denmark