Monograph
J01CF02 - Cloxacillin |
Not porphyrinogenic |
NP |
Rationale
Metabolised only to a limited extent. Two references state non-porphyrinogenicity.
Chemical description
Penicillinase stable penicillin used parenterally (up to 2 g x 3) in staphylococcal infections mainly eliminated in unchanged form by renal ecxretion. No clear data pointing to CYP-interaction. Half life in blood is 30 minutes, 30-50 % of the dose being excreted within 6 hours. South African list: use. Australian list: safe.
Similar drugs
Tradenames and packages
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