Monograph
J01DD08 - Cefixime |
Propably not porphyrinogenic |
PNP |
Rationale
Probably not significantly metabolised. Conflicting references.
Chemical description
Perorally administered cephalosporin (200 mg x 2) used in pharyngotonsillitis, otitis media and sinusitis where treatment with penicillins have shown to be without effect. About 20 % of an oral dose (or 50 % of the absorbed dose) is excreted unchanged in urine within 24 hours. Up to 60% may be eliminated by non-renal mechanisms. There is no evidence of metabolism but some of the drug is probabably ecreted via bile. South African list: use with caution . French list: use.
IPNet drug reports
Uneventful use reported in 2 patients with acute porphyria.
Similar drugs
Tradenames and packages
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