Aminoglycoside, not metabolised. Three references state non-porphyrinogenicity.

Broadspectrum aminoglycoside antibiotic. Eliminated in unchanged form by glomerular filtration. South African list: use. French list: use. Moore, Hift 1997: safe.

One very well documented report of an attack requiring hospitalisation and treatment with heme arginate in a 39 year old susceptible female with AIP. However the patient also had an infection with fever that just as well could have caused the attack. Uneventful use reported in 4 patients with acute porphyria.