Hydrophilic steroid structure. May act as a CYP inducer on prolonged (> 2 weeks) use. Several references: safe/use

Antibacterial steroid used in staphylococcal infections. Excreted in bile after oxidative metabolism and glucuronidation. CYP-induction demonstrated not after 14 days, but after one month of therapy. French list: use. South African list: use. Australian list: safe. Peters:

Uneventful use reported in 1 patient with acute porphyria.