Monograph

J01XX05 - Methenamine

Not porphyrinogenic

Rationale

Water-soluble organic salt. Two references consider it safe. Several observations of non-porphyrinogenicity.

Chemical description

Metenamine hippurate, Largely excreted unchanged but hydrolyzed in the urinay tract to formaldehyde and ammonia, excreted in urine. Previously often in use in acute porphyrias as an antibacterial agent in urinary tract infections. Probably without CYP affinity. South African list: use. Metabolic Basisâ€¦ref 279: probably safe. Thunell: On many occasions observed to be tolerated.

IPNet drug reports

Uneventful use reported in 1 patient with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes J01X / J01XX or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands