Limitations: This safety classification applies only to preparations containing a combination of the two drugs diclofenac and misoprostol. The same ATC-code (M01A B55) can in some countries be used for different combinations of diclofenac and other drugs, which in theory may be porphyrinogenic. Please refer to the classification and monograph of each individual substance. If the combination contains a substance which is not classified (NC) or has been classified as porphyrinogenic (PSP, PRP or P), the safety classification of such a combination as PNP is no longer valid. Combination products which contains the two substances diclofenac (ATC code: M01A B05) and misoprostol (ATC code: A02B B01) are safety classified as Probably not porphyrinogenic (PNP), as both of them are safety classified as Probably not porphyrinogenic (PNP) separately. For more details please refer to the monographs of the two substances.