Monograph
A06AD15 - Macrogol |
Not porphyrinogenic |
NP |
Rationale
Macrogols are not absorbed from the gastrointestinal tract.
Chemical description
Mixtures of long, linear polymers.
Therapeutic characteristics
Macrogols are used as osmotic laxatives. A solution of macrogol 3350 (or 4000) is used for the treatment of chronic constipation in a usual oral dose of 125 mL up to three times daily. Common adverse reactions of macrogols that can be confused with an acute porphyric attack are gastrointestinal discomfort, bloating, and nausea.
Metabolism and pharmacokinetics
Not absorbed from the garstrointerstinal tract, eliminated in feces.
IPNet drug reports
Uneventful use reported in 2 patients with acute porphyria.
Similar drugs
References
| # | Citation details | PMID |
|---|---|---|
| * | Drug reference publications | |
| 1. | Sweetman SC, editor. Martindale: The complete drug reference. Macrogols. Pharmaceutical Press 2009.
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Tradenames
This list comprises raw data collected from different countries.
In some cases, a more comprehensive list of available drug packages is included.
Consequently, very similar terms may therefore appear multiple times.
Bold names are the searchable terms, while the gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors.
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Casenlax 10 g, poeder voor drank · Casenlax 4 g, poeder voor drank · Forlax Junior 4 g, poeder voor drank in sachet 4 g · Forlax 10 g, poeder voor drank in sachet · Forlax 10 g, poeder voor drank in sachet 10 g · Forlax 10 g, poeder voor drank in sachets · Forlax Junior 4 g, poeder voor drank in sachet · Macrogol Aurobindo 4 gram, poeder voor drank in sachet · Macrogol Eureco-Pharma 10 g, poeder voor drank in sachet · Macrogol Sanias 10 gram, poeder voor drank in sachet · Macrogol Strides 10 g poeder voor drank in sachet · Macrogol Strides 4 g poeder voor drank in sachet · Macrogol Top-Pharma 10 g, poeder voor drank in sachet 
Forlax 10 g sol. buv. (pdr.) sachet · Forlax Junior 4 g sol. buv. (pdr.) sachet · Macrogol AB 10 g sol. buv. (pdr.) sachet · Macrogol AB 4 g sol. buv. (pdr.) sachet · Transilax 10 g sol. buv. (pdr.) sachet · Transilax 4 g sol. buv. (pdr.) sachet · Transisoft 8.5 g sol. buv. (pdr.) sachet 
CASENLAX 10 g POLVO PARA SOLUCION ORAL EN SOBRE · Casenlax 10 g Solucion Oral en Sobre · CASENLAX 4 g POLVO PARA SOLUCION ORAL EN SOBRES · Casenlax 500 mg/ml Solucion Oral · Femlax 10 g Polvo Para Solucion Oral en Sobres · Macrogol · Macrogol Aurovitas 10 g Polvo Para Solucion Oral en Sobre · Micralax Macrogol 5,9 g Polvo Para Solucion Oral · Omnilax 10 g Polvo Para Solucion Oral en Sobre · Omnilax 4 g Polvo Para Solucion Oral en Sobre 
FORLAX 10 g · PROCTOLAX 10 g · PROCTOLAX 4 g 
Dulcobalance · Idrolax · TransiSoft 
Casenlax · Macrogol 4000 Strides 
Forlax · Macrogol 4000 caelo 
Forlax 10 g · Macrogol Aurovitas · Olopeg · Pegorion · Pegorion Junior 
Forlax · Forlax Junior · Transilax 
Casenlax · Makrogoli Orion · Pegorion · Pegulos · Smoothlax 
Forlax · Proctolax 
Casenlax
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