N02AA03 - Hydromorphone |
Probably not porphyrinogenic |
PNP |
Rationale
Opioid. References state non-porphyrinogenicity.
Chemical description
Opioid analgesic metabolized to a large extent and excreted in urine in conjugated form. Anderson KE: Effects of antihypertensive drugs on hepatic heme biosynthesis, and evaluation of ferrochelatase inhibitors to simplify testing of drugs for heme pathway induction.Biochem Biophys Acta 543:313, 1978: safe. Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997: probably safe.
IPNet drug reports
Uneventful use reported in 1 patient with acute porphyria.
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Drugs in the acute porphyrias--toxicogenetic diseases.
Moore MR, Hift RJ. Cell Mol Biol (Noisy-le-grand). 1997 Feb; 43(1):89-94.
|
9074793 |
Tradenames
Hydagelan · Hydromorfonhydrochloride · Palladon 
Palladone 
Sophidone 
Edunix · Hidromorfona · Jurnista · Palladone 
Medepidol 
Hydromorphone · Hydromorphoni · Palladon 
Hydromorphone · Palladone 
Hydofon · Hydromorphonhydrochlorid · Palladon 
Extempore N02AA03 Hydromorfon · Hydofon · Hydromorfon · Hydromorfonhydroklorid · Hydromorphone · Palladon 
Hydofon · Palladon · Palladone 
Hidromorfona 
Dilaudid · Dilaudid-HP 
Dilaudid · Hydromorph Contin · Hydromorph Contin-Controlled cap · Hydromorphone · Hydromorphone Forte 
Hydromorphon · Palladone 
Hydofon · Hydromorphone · Palladon 
Hydromorphone · Palladon 
Hydromorphone 
Hydromorphone · Jurnista 
Jurnista · Palladone 
Palladone 
Dilaudid 
Hidromorfona 
Hydromorphone