Monograph
N05AB02 - Fluphenazine |
Not porphyrinogenic |
NP |
Rationale
Substrate of CYP 2D6. Inhibitor of CYPs 2D6, 1A2, 2E1, 3A4. Several references state non-porphyrinogenicity (phenothiazines in general).
Chemical description
Low-dose phenothiazine neuroleptic used in manic and psychotic conditions Metabolized by CYP 2D6. No data indicating CYP-induction. MFM James, RJ Hift. Porphyrias. Br J Anaesth 2000; 85, 143-53: use (phenothiazines). Australian list: safe EPI-list: safe South African list: use French list: use (fluphenazine) Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997: safe
Similar drugs
Tradenames and packages
From some sources, we get a list of packages (United Kingdom, Ireland, Estonia).
Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway).
What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names
are the searchable terms. The gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors.
We strive to improve it continuously.
United Kingdom
Norway
Serbia© NAPOS 2024