Synthetic opiate, some systemic absorption takes place. Probably CYP-metabolised. No data pointing to CYP-induction. Two references state non-porphyrinogenicity.
Chemical description
Synthetic opiate used in diarrhoea. Metabolized by oxidative N-demethylation. No data given on CYP-interaction, South African list: use. French list: authorized
IPNet drug reports
Uneventful use reported in 17 patients with acute porphyria.
Similar drugs
Explore alternative drugs in similar therapeutic classes
A07D /
A07DA or
go back.