Monograph

A07EC02 - Mesalazine

Propably not porphyrinogenic

Rationale

Relatively low systemic exposure of substance with probably non-CYP metabolism. Acetyl salicylic acid is an inducer of CYP 2C19. Two references state non-porphyrinogenicity.

Chemical description

5-aminosalicylic acid (5-ASA). Antiinflammatory agent in suppositorium or foam for local rectal use, 1 g/d. Low systemic exposure, only about 20 % of the given dose recovered in urine after acetylation in the intestinal mucosa and the liver. South African list: use. EPI-list: use

IPNet drug reports

Uneventful use reported in 6 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes A07E / A07EC or go back.

Tradenames and packages

From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.

Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.

Netherlands

Asacol · Asacol 400 tablet, maagsapresistente tabletten 400 mg · Asacol 800 tablet, maagsapresistente tabletten 800 mg · Azzavix · Azzavix 1000 mg maagsapresistente tabletten · Colitofalk · Colitofalk 1 g, zetpillen · Kiudro · Kiudro 1 g zetpil · Mesalazine · Mesalazine Aurobindo 500 mg, zetpillen · Mesalazine Aurobindo EC 250 mg, maagsapresistente tabletten · Mesalazine Aurobindo EC 500 mg, maagsapresistente tabletten · Mesalazine BModesto 1200 mg, maagsapresistente tabletten met verlengde afgifte · Mesalazine ERC 1200 mg maagsapresistent, tabletten met verlengde afgifte · Mesalazine Faes 500 mg maagsapresistente tabletten · Mesalazine Medcor 1200 mg, maagsapresistente tabletten met verlengde afgifte · Mesalazine Nordic 750 mg, maagsapresistente tabletten · Mesalazine Nordic EC 250, maagsapresistente tabletten 250 mg · Mesalazine Nordic EC 500, maagsapresistente tabletten 500 mg · Mesalazine Sandoz tablet EC 250, maagsapresistente tabletten 250 mg · Mesalazine Sandoz tablet EC 500, maagsapresistente tabletten 500 mg · Mesavancol · Mesavancol 1200 mg maagsapresistent, tabletten met verlengde afgifte · Mezavant · Mezavant 1200 mg maagsapresistente, tabletten met verlengde afgifte · Mezavant 1200 mg, maagsapresistente tabletten met verlengde afgifte · Pentasa · Pentasa 1 g zetpillen · Pentasa 1 g, tabletten met verlengde afgifte · Pentasa 1g, tabletten met verlengde afgifte · Pentasa 1g/100 ml, suspensie voor rectaal gebruik · Pentasa 500 mg, tabletten met verlengde afgifte · Pentasa sachet 1 g, granulaat met verlengde afgifte · Pentasa sachet 2 g, granulaat met verlengde afgifte · Pentasa sachet 4 g, granulaat met verlengde afgifte · Pentasa Compact · Pentasa Compact 1 g, granulaat met verlengde afgifte · Pentasa Compact 1g, granulaat met verlengde afgifte · Pentasa Compact 2 g, granulaat met verlengde afgifte · Pentasa Compact 4 g, granulaat met verlengde afgifte · Salofalk · Salofalk 1,5 g Granu-Stix, granulaat met verlengde afgifte · Salofalk 1,5g Granu-Stix, granulaat met verlengde afgifte · Salofalk 1000 mg Granu-Stix, granulaat met verlengde afgifte · Salofalk 1000 mg Granu-Stix, maagsapresistent granulaat met verlengde afgifte · Salofalk 1g, zetpillen · Salofalk 2 g/30 g, klysma · Salofalk 2 g/60 g, klysma · Salofalk 250, maagsapresistente tabletten 250 mg · Salofalk 3 g Granu-Stix, granulaat met verlengde afgifte · Salofalk 4 g/60 g, klysma · Salofalk 500 mg Granu-Stix, granulaat met verlengde afgifte · Salofalk 500, maagsapresistente tabletten 500 mg · Salofalk Schuim 1 g/dosis, schuim voor rectaal gebruik · Salofalk zetpil 250, zetpillen 250 mg · Salofalk zetpil 500, zetpillen 500 mg · Yaldigo · Yaldigo 1600 mg, tabletten met gereguleerde afgifte

Belgium

Asamovon · Asamovon 1 600 mg compr. lib. modif. · Claversal · Claversal 1 g mousse rect. récip. multidos. · Claversal 500 mg compr. gastro-résist. · Claversal 500 mg supp. · Colitofalk · Colitofalk 1 000 mg gran. gastro-résist. lib. prol. sachet · Colitofalk 1 g supp. · Colitofalk 1.5 g gran. gastro-résist. lib. prol. sachet · Colitofalk 2 g susp. rect. · Colitofalk 3 g gran. gastro-résist. lib. prol. sachet · Colitofalk 4 g susp. rect. · Colitofalk 500 mg gran. gastro-résist. lib. prol. sachet · Mesalazine · Mesalazine Teva 500 mg compr. gastro-résist. · Mezavant · Mezavant 1 200 mg compr. lib. prol. · Pentasa · Pentasa 1 g compr. lib. prol. · Pentasa 1 g supp. · Pentasa 1 g/100 ml susp. rect. · Pentasa 500 mg compr. lib. prol. pot · Pentasa Sachet 1 g gran. lib. prol. sachet · Pentasa Sachet 2 g gran. lib. prol. sachet · Pentasa Sachet 4 g gran. lib. prol. sachet

United Kingdom

Asacol · Asacol 1g/application foam enema · Asacol 250mg suppositories · Asacol 400mg MR gastro-resistant tablets · Asacol 500mg suppositories · Asacol 800mg MR gastro-resistant tablets · Ipocol · Ipocol 400mg gastro-resistant tablets · Mesalazine · Mesalazine 1g/application foam enema · Mesalazine 250mg suppositories · Mesalazine 2g/59ml enema · Mesalazine 300mg/5ml oral suspension · Mesalazine 400mg gastro-resistant tablets · Mesalazine 400mg/5ml oral solution · Mesalazine 400mg/5ml oral suspension · Mesalazine 500mg suppositories · Mesalazine 500mg/5ml oral solution · Mesalazine 500mg/5ml oral suspension · Mesalazine 800mg gastro-resistant tablets · Mesren MR · Mesren MR 400mg gastro-resistant tablets · Mezavant · Mezavant XL 1200mg tablets · Octasa · Octasa 1600mg MR gastro-resistant tablets · Octasa 1g suppositories · Octasa 400mg MR gastro-resistant tablets · Octasa 800mg MR gastro-resistant tablets · Pentasa · Pentasa 1g modified-release granules sachets · Pentasa 1g modified-release tablets · Pentasa 1g suppositories · Pentasa 2g modified-release granules sachets · Pentasa 4g modified-release granules sachets · Pentasa 500mg modified-release tablets · Pentasa Mesalazine · Pentasa Mesalazine 1g/100ml enema · Salcrozine · Salcrozine 1000mg gastro-resistant tablets · Salcrozine 500mg gastro-resistant tablets · Salofalk · Salofalk 1.5g gastro-resistant modified-release granules sachets · Salofalk 1g gastro-resistant modified-release granules sachets · Salofalk 1g gastro-resistant tablets · Salofalk 1g suppositories · Salofalk 1g/application foam enema · Salofalk 250mg gastro-resistant tablets · Salofalk 2g/59ml enema · Salofalk 3g gastro-resistant modified-release granules sachets · Salofalk 500mg gastro-resistant modified-release granules sachets · Salofalk 500mg gastro-resistant tablets · Salofalk 500mg suppositories · Zintasa · Zintasa 400mg EC tablets

Denmark

Asacol · Mesalazin · Mesalazin "2care4" · Mesalazin "Orion" · Mesavancol · Mezavant · Pentasa · Pentasa Sachet · Quintasa · Quintasa Sachet · Salofalk

Norway

Asacol · Mesalazin Orion · Mesalazina doc · Mezavant · Pentasa · Pentasa Sachet · Salofalk

Poland

Asamax 250 · Asamax 500 · Crohnax · Mezavant · Pentasa · Salaza · Salofalk · Salofalk 1 g · Salofalk 500

Luxembourg

CLAVERSAL · COLITOFALK · COLITOFALK-1,5 · COLITOFALK-1000 · Colitofalk-3 · COLITOFALK-500 · MEZAVANT · MEZAVANT-1200 · Pentasa · SALOFALK

Iceland

Asacol · Pentasa · Pentasa Sachet

Finland

Asacol · Mesalazin Orion · Pentasa · Salofalk

Latvia

Asacol · Pentasa · Salofalk · Yaldigo

Serbia

5-ASA · 5-ASA® · Asacol · Asacol® · Pentasa · PENTASA® · Salofalk · Salofalk® · Salofalk® 500

Acute Porphyria Drug Database

Monograph