Acute Porphyria Drugs

P01BA02 - Hydroxychloroquine

Possibly porphyrinogenic
PSP

Rationale
Partly CYP-metabolised. Compare the 8-aminoquioline primaquine: Inducer of CYPs 1A1, 1A2 and 1B1.
Chemical description
Aminokinoline derivative used in sensitive malaria strains. Administered as tablets in a three-day cure starting with 1200 mg the first day. Vast tissue distribution with accumulation in blood cells and in liver, lungs, kidneys and eyes. Partly converted by CYP 2D6 to de- ethylated metabolites. Slowly excreted with a terminal half life of 50 days. About 25% excreted by the kidneys in unchanged form.
Similar drugs
Explore alternative drugs in similar therapeutic classes P01B / P01BA or go back.
References
Tradenames

Hydroxychloroquine · Plaquenil Plaquenil Dolquine · Duplaxil · Hidroxicloroquina Hidroxiklorokin · Plaquenil Idrossiclorochina · Plaquenil Plaquenil Hydroxychloroquine · Plaquenil Hydroxychloroquine · Plaquenil · Quinoric Pimaxiro · Plaquenil Hydroxychloroquine · Pimaxiro · Plaquenil Autokila · Hydroquenin · Hydroxychloroquine · Novidin Dimard · Hcqs · Hidroxicloroquina · Malarquin · Plaquinol Hydroxychloroquine · Hydroxyquine · Plaquenil Plaquenil Plaquenil Oxiklorin Hcqs · Hydroxychloroquine · Plaquenil · Zy-Q Plaquenil Hydroxychloroquine · Plaquenil Hyplaxy Hidroksiklorokinijev · Hydroxychloroquine · Hyplaxy · Plaquenil · Quinoric Hidroxicloroquina Hydroxychloroquine
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