R01AD01 - Beclometasone

Not porphyrinogenic

Rationale

Inducer of CYP 3A5. Probably no significant systemic exposure. Several references stating non-porphyrinogenicity of glucocorticoids.

Chemical description

Antiinflammatory halogenated glucocorticoide for local (nasal spray) treatment of allergic and vasomotor rhinitis. Low probability for systemic effects. EPI-list: safe. French list: authorized. South African list: use Kalman, Bonkowski: safe The Merck Manual: safe Tschudy DP, Lamon JM: Porphyrin metabolism and the porphyrias, in Bondy PK, Rosenberg LE (eds.): Duncans Diseases of Metabolism. Philadelphia, WB Saunders, 1980, p939: safe Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997: safe

IPNet drug reports

Uneventful use reported in 6 patients with acute porphyria.

Similar drugs

Explore alternative drugs in similar therapeutic classes R01A / R01AD or go back.

References

#	Citation details	PubMed ID
1.	Management of acute attacks in the porphyrias. Kalman DR, Bonkovsky HL. Clin Dermatol. 1998; 16(2):299-306.	9554242
2.	Drugs in the acute porphyrias--toxicogenetic diseases. Moore MR, Hift RJ. Cell Mol Biol (Noisy-le-grand). 1997 Feb; 43(1):89-94.	9074793
Other sources
3.	Porphyrin metabolism and the Porphyrias [Book Chapter] Tschudy DP, Lamon JM Bondy BK, Rosenberg LE (eds): Duncan's Diseases of Metabolism, Philadelphia, WB Saunders. 1980.

Tradenames

Show more details and information about the listed tradenames

Beclometason

Beclo Rhino · Beconase · Rhinomaxil · Rinoclenil

Beclo-Rino · Beconase Acuoso

Beclonasal

Beclometasone · Becotide · Rinoclenil · Turbinal

Rinoclenil

Otri Heuschnupfen

Beclo-Aqua · Beclometasone · Beclometasone Hayfever Relief · Beconase Aqueous · Beconase Hayfever · Beconase Hayfever Relief for Adults · Care Hayfever Relief · Nasobec Aqueous · Nasobec Hayfever · Numark Hayfever Relief · Pollenase Hayfever · Pollenase Hayfever Relief for Adults · Rino Clenil · Vivabec