R03AC12 - Salmeterol |
Propably not porphyrinogenic |
PNP |
Rationale
Substrate for CYP 3A4. Probably insignificant metabolic load.
Chemical description
Adrenergic administered in asthma in inhalation aerosol, 50 µg/dose. Gives rise only to very low plasma concentrations. Metabolized in the liver (CYP 3A4) producing several metabolites.
IPNet drug reports
Uneventful use reported in 4 patients with acute porphyria.
Similar drugs
References
Tradenames
Serevent 
Serevent 
Beglan · Betamican · Inaspir · Serevent · Soltel 
Serevent 
Salmetedur · Serevent 
Serevent 
Neovent · Salmeterol · Serevent · Soltel · Vertine 
Salmeterol · Serevent 
Serevent 
Asmetic · Pulmoterol · Pulveril · Serevent 
Serevent 
Serevent 
Serevent 
Salmeterol · Serevent 
Salmeterol · Serevent 
Serevent 
Serevent 
Serevent 
Serevent 
Beglan · Neovent · Serevent · Soltel · Vertine 
Salmeterol