Acute Porphyria Drug Database

Monograph

R06AD52 - Promethazine, Combinations
Possibly porphyrinogenic
PSP

Rationale
Promethazine is clinically observed to be unsafe (one report), stated to be safe in three references.
Chemical description
Aniemetic. The sedative effect of promethazine is lessened by caffeine. Its effect on motion sickness is enhanced by caffeine and ephedrine. ephedrine: South African list: safe EPI-list: safe Kalman, Bonkowsky: safe promethazine: South African list: use French list: authorized EPI-list: safe Shonfeld: observed to be extremely unsafe.

Similar drugs
Explore alternative drugs in similar therapeutic classes R06A / R06AD or go back.

Tradenames and packages
From some sources, we get a list of packages (United Kingdom, Ireland, Estonia). Other sources contain more or less "clean" versions of the trade name (Denmark, Finland, Iceland, Lithuania, Norway). What you see here is the raw data we get from each country, so there will appear to be duplicates. The bold names are the searchable terms. The gray names that follow are all mapped to the bolded term.
Note: The cleaning is done automatically by a proprietary algorithm, and it may produce errors. We strive to improve it continuously.
United Kingdom
Tixylix ยท Tixylix Night Cough oral solution
 
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