Monograph
S02BA07 - Betamethasone |
Propably not porphyrinogenic |
PNP |
Rationale
Probably only restricted absorption. Glucocorticoids: Several references: use/authorised/safe. Isopropanol: Possibly porphyrinogenic in heavy exposure.
Chemical description
Strong glucocorticoid administered as ear drops in aqueous isopropanol solution. used in external otitis. South African list: use French list: authorized Kalman, Bonkowski: safe Tschudy DP, Lamon JM: Porphyrin metabolism and the porphyrias in Bondy PK, RosenbergLE (eds.): Duncan's Disease of metabolism. Philadelphia, WB Saunders,1980, p 939: safe Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997 : safe
Similar drugs
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