S02BA07 - Betamethasone |
Probably not porphyrinogenic |
PNP |
Rationale
Probably only restricted absorption. Glucocorticoids: Several references: use/authorised/safe. Isopropanol: Possibly porphyrinogenic in heavy exposure.
Chemical description
Strong glucocorticoid administered as ear drops in aqueous isopropanol solution. used in external otitis. South African list: use French list: authorized Kalman, Bonkowski: safe Tschudy DP, Lamon JM: Porphyrin metabolism and the porphyrias in Bondy PK, RosenbergLE (eds.): Duncan's Disease of metabolism. Philadelphia, WB Saunders,1980, p 939: safe Moore MR, Hift RJ: Drugs in the acute porphyrias. Cell Mol Biol 43:89, 1997 : safe
Similar drugs
References
| # | Citation details | PubMed ID |
|---|---|---|
| 1. | Management of acute attacks in the porphyrias.
Kalman DR, Bonkovsky HL. Clin Dermatol. 1998; 16(2):299-306.
|
9554242 |
| 2. | Drugs in the acute porphyrias--toxicogenetic diseases.
Moore MR, Hift RJ. Cell Mol Biol (Noisy-le-grand). 1997 Feb; 43(1):89-94.
|
9074793 |
| Other sources | ||
| 3. | Porphyrin metabolism and the Porphyrias [Book Chapter]
Tschudy DP, Lamon JM Bondy BK, Rosenberg LE (eds): Duncan's Diseases of Metabolism, Philadelphia, WB Saunders. 1980.
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Tradenames
Diprotit 
Diprotit