V03AF05 - Amifostine |
Not porphyrinogenic |
NP |
Rationale
Non-CYP metabolism.
Chemical description
Organic thiophosphate used as a cytoprotective during treatment with cyclophosphamide combined with cisplatine in advanced ovarial cancer. Prodrug, rapidly metabolized by alcaline phosphatase to free phosphatase and the active free thiol.
Similar drugs
References
Tradenames
Ethyol 
Ethyol 
Amifostine · Ethyol 
Amifostina 
Amifostine