Acute Porphyria Drugs

C01CA01 - Etilefrine

Probably not porphyrinogenic
PNP

Rationale
Non-CYP metabolism. No data pointing to CYP-interaction.
Chemical description
Structurally related to endogenous adrenaline, lacking one catechol-hydroxy moiety, and N-ethyl substituent instead of N-methy.
Therapeutic characteristics
Adrenergic substance used in hypotension.
Metabolism and pharmacokinetics
Metabolized by conjugation to sulfates and glucuronides and by deamination to hydroxymandelic acid.
Personal communication
None
Published experience
None
Similar drugs
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References
Tradenames

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